Natural selection of triclosan resistant bacteria natural selection is a mechanism of evolution dependent on the environmental. How antibiotic resistance happens the pew charitable trusts. Use data evidence to make claims about variation, fitness, selection and evolution in populations. This is because increases in antibiotic resistance are driven by a combination of germs exposed to antibiotics, and the spread of those germs and their mechanisms of resistance. Davies j and davies d 2010 origins and evolution of antibiotic. Regulating evolutionarticle from scientific american may 2008.
Antibiotic resistance encompasses one of the worlds most pressing public health problems. Tracking the spread of antibiotic resistance student handout pdf. Antibiotics ebug young adult contents this pack contains a series of educational resources for young adults aged 1518 years on the topic of antibiotics and antibiotic resistance. Antibiotics ebug young adult contents this pack contains a series of educational resources for young adults aged 1518 years on the topic of. Anytime antibiotics are used, they can contribute to antibiotic resistance.
Evolution of antibiotic resistance this unit is actually more of a miniunit, embedded within a larger unit on evolution, or more specifically, microevolution. Antibiotic resistance threats in the united states, 20. Free pdf download of ncert solutions class 12 biology chapter 7 evolution solved by expert teachers at coolgyan as per ncert cbse textbook guidelines. This video describes how widespread use of antibiotics in medicine, agriculture, and household products can lead to the evolution of microbes that are resistant to multiple antibiotics. Tackling antibiotic resistance is a high priority for who. This lesson addresses next generation science standards ngss. Antibiotic resistance will eventually occur because of evolutionary natural selection, but the. Mrsa is a type of staphylococcus staph bacteria that is resistant to almost all antibiotics.
Young scholars investigate the increasing problem of antibiotic resistance in such menacing diseases as tuberculosis and influenza. Walk around and listen to students comments as another way to determine if students did gain an understanding about the role of evolution in antibiotic resistance, how antibiotic resistance expands and why this is a problem. Displaying all worksheets related to evolution of antibiotic resistance. The second activity is a survey about antibiotic usemisuse that students are to conduct in their neighborhoods. They take on the role of staff at a public health agency who are trying to communicate the problem to the public. Antibiotic resistance you can watch all my videos at. Antibiotics and antibiotic resistance antibiotics are antibacterial biological substances produced by other microorganisms actinomycetesfungi whereas chemotherapeutic agent is synthetically produced. The % prescription rates are for all antibiotics across wales in 2008.
Lesson plans, worksheets and activities for 1518 year olds on antibiotics and antibiotic resistance. However, even back then, fleming knew that bacteria could become resistant to penicillin. Superbugs that resist antibiotics can evolve in 11 days. Antibiotics and evolution part i the rise of the super bug i was sitting in a hospital bay and i wasnt really worried. The emergence of antimicrobial resistance is a major global threat to modern medicine. They answer a series of questions that guides them toward the understanding that the rise of antibiotic resistant bacteria within the population is an example of evolution by natural selection. Genome sequence analyses of environmental microbes revealed that they are replete with. How is the emergence of antibioticresistant bacteria an example of natural selection. This is a really important topic as antibiotic resistant diseases such as mrsa present a real problem for hospitals. Before class, students work on a just in time teaching jitt assignment that involves reading an.
Antibiotics such as chloramphenicol and erythromycin are derived from other bacteria or fungi. Ask students how might antibiotic resistance be evidence to support evolution or in other words why would it be beneficial for bacteria to have antibiotic resistance. Worksheets are e bug, activity work the problem with antibacterial, lesson 11 antibiotics and evolution, tcss biology unit 4 evolution information, darwin 2009 natural selection, teacher activity resource high school biologyhealth, evolution answers work, vgec teacher work. What is antibiotic resistance and how do bacteria develop it. Finally, discuss with student how antibiotic resistance might be an excellent adaptation for survival in bacteria. If either patient is resistant, it will be important to change to a different antibiotic as soon as possible. Distinguish between evolution and natural selection.
It happens when you have bergers disease, a type of autoimmune thing that aff ects the kidney, so that you have to get dialysis to. This quiz and corresponding worksheet will test you on your knowledge. When antibiotics are needed, the benefits usually outweigh the risks of antibiotic resistance. Explain how the antibioticresistant mrsa bacteria are used as evidence to support darwins theory of evolution by natural selection. Click here to get best class 12 biology all chapter 7 evolution exercises questions with solutions to help you to revise complete syllabus and boost your score more in examinations. The bacteria survive and continue to multiply causing. Antibiotics, such as penicillin, are drugs that kill or prevent the growth of bacteria.
Any one specific resistance mechanism can often be acquired by multiple types of genetic changes multiple color arrows often lead to the same type of resistance mechanism. The first activity involves two videos freely available on the website, followup questions, and classroom discussion. To answer these questions, we need to understand how antibiotic resistant bacteria arise, and. However, the majority of antibiotic resistances are most likely cases of acquired resistance, through the lateral transfer of antibiotic resistance genes from other ecologically and taxonomically distant bacteria.
Nova sciencenow teachers classroom activity killer. Natural selection and the development of antibiotic resistance middle. The global action plan aims to ensure prevention and treatment of infectious diseases with safe and effective medicines. Predicting the evolution of antibiotic resistance bmc. This raises several questions about the evolution and ecology of antibiotic resistance genes. Show the animation evolution of antibiotic resistance and then ask students to describe the animations key points. Perhaps the most bizarre objection to evolution i have ever heard is that mutation cant increase information in the genome, as though there were some sort of law of nature, part of the science known as information theory, that made the increase of information in the genome impossible. Surprisingly, a new study found that bacteria adapting to increased temperature became resistant to rifampicin.
Students will evaluate the role of natural selection in the development of the theory of evolution. Evolution and antibiotic resistance lesson plan for 9th. Regulating evolution article from scientific american may 2008. Nova sciencenow teachers classroom activity killer microbe. Suppression of antibiotic resistance evolution by single.
Antibiotic resistance occurs when bacteria change in some way that reduces or eliminates the effectiveness of drugs, chemicals, or other agents designed to cure or prevent infections. Apr 23, 20 antibiotic resistance threats in the united states, 20. Origins and evolution of antibiotic resistance microbiology. Ncert solutions for class 12 biology chapter 7 evolution. Antibiotics teacher answer sheet ebugyoung adult atb ts9 2. Working in pairs, students then model what happens to the gut microbiome when exposed to multiple rounds of antibiotic treatment. Apply the general definition of natural selection to explain the evolution of antibiotic resistance in bacteria populations. Pdf antibiotic resistance and the biology of history. Antibiotic treatment generally results in the selection of resistant bacterial strains, and the dynamics of resistance evolution is dependent on complex interactions between cellular components. This page contains three student activities for learning about evolution of antibiotic resistance. Gather information about the use and misuse of antibiotics in your own neighborhood. Antibiotic resistance is the ability of bacteria or other microbes to resist the effects of an antibiotic. Public broadcasting service in this lesson plan for high school, students investigate the growing problem of antibiotic resistance. A global action plan on antimicrobial resistance, including antibiotic resistance, was endorsed at the world health assembly in may 2015.
In under 100 years, we have gone from virtually no widespread antibiotic resistance to a world where antibiotic resistance is so widespread that it is. Teacher worksheet antibiotics and resistance activity intended learning outcomes to understand how antibiotics are used to treat infections to understand how misuse of antibiotics can lead to antibiotic resistant infections materials a student volunteer. The simulation uses dice and inexpensive pony beads to model the evolution of bacteria over a course of antibiotics. The information on the molecular changes involved in antibiotic resistance that will result from these endeavors will feed models of evolution that can incorporate observed patterns of pleiotropy and epistasis and explore the consequences under various population dynamic scenarios. Antibiotic resistance is one of the clearest examples of evolution by natural selection that humans have been able to view in real time. The evolution of bacteria on a megaplate petri dish kishony lab. This evolution and antibiotic resistance lesson plan is suitable for 9th 12th grade. Students could then research the symptoms of infection. Antimicrobial resistance world health organization. Consistent with the concept of the recent evolution of antibiotic resistance plasmids and multiresistant strains, studies with collections of bacterial pathogens isolated before the antibiotic era showed that plasmids were common but r genes were rare.
By studying the consequences of the involved mutations in different conditions and genetic backgrounds, the authors illustrate how knowledge of two fundamental genetic properties. The overriding purpose of this report is to increase awareness of the threat that antibiotic resistance poses and to encourage immediate action to address the. Mutations causing antibiotic resistance are often associated with a cost in the absence of antibiotics. Ninth grade lesson antibiotic resistance betterlesson. Evolution and ecology of antibiotic resistance genes fems. Carls work tackles the very real problem of the evolution of antibiotic resistance by bacterial populations in hospitals. The data in table 2 shows antibiotic prescription rates and % resistance for the 1524 age group. Students will investigate the theory of evolution and how it pertains to the biological history of earth. This website and its content is subject to our terms and conditions.
Since antibioticresistant staph infections can get worse quickly, your team has been asked to test the bacteria from both patients for resistance to penicillin. Antibiotic resistance and natural selection in education. Kevin wu details the evolution of this problem that presents a big challenge for the future of medicine. Antibiotic resistance and bacterial evolution bitescis. To combat this, the current strategy is primarily focused on developing new antibiotic agents or. Key words antibiotic resistance, mutation, microbiome. A complete explanation should mention that the graphs show when the bacteria acquired resistance to antibiotics a and c and how the proportion of antibioticresistant and nonresistant bacteria change over the six days. A complete explanation should mention that the graphs show when the bacteria acquired resistance to antibiotics a and c and how the proportion of antibiotic resistant and nonresistant bacteria change over the six days. Population diversity and the evolution of antibiotic resistance. In under 100 years, we have gone from virtually no widespread antibiotic resistance to a world where antibiotic resistance is. Antibiotic resistance and natural selection igcse biology.
The students are challenged with a very topical and relevant problem. It was appealing because it connects antibiotic resistance directly with something that nearly all students have done. This question is explained in the answer to student sheet question 11. We demonstrate this principle by notable examples from both clinic and laboratory evolution pertaining to each of the four lines of defense. Evolution of antibiotic resistance worksheets lesson. The video explains how antibiotics work and why humans are becoming resistant to them.
Dec 20, 2017 it was appealing because it connects antibiotic resistance directly with something that nearly all students have done. Digital comprehensive summaries of uppsala dissertations from the faculty of medicine 1150. Table 2 antibiotic % resistance for 1524 age group % of total prescriptions amoxicillin 49. In this task, you are challenged to understand exactly what is going on in a bacterial population that is now resistant to an antibiotic to which it had previously been susceptible. Natural selection and the development of antibiotic resistance. Antibiotic resistance in bacterial infections is a serious problem that is only getting worse. Tes global ltd is registered in england company no 02017289 with its registered office at 26 red lion square london wc1r 4hq. Teacher activity resource sheet high school biologyhealth. Activity 1 graphing antibiotic effectiveness 2 pages. Evolution by natural selectionbacterial resistance worksheet. Tes global ltd is registered in england company no 02017289 with its registered office. Survey form pdf, or obtain a copy from your teacher. This resource focuses on the biological concepts of immune system function, the evolution of antibiotic resistance in a population of bacteria, and the process of designing a controlled experiment, teachers guide not shown.
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